Dataset for "Preservation Of β Cell Mass by Targeting Fatty Acid Oxidation in Islet Macrophages Mechanisms and Therapeutic Interventions"

In this study, we aimed to investigate the possible role of CPT1a in macrophage function and polarization, and the role of islet resident macrophage in beta cell proliferation. This dataset includes phenotype information of the MKO (macrophage specific Cpt1a knockout) mice model, including bodyweight, glucose tolerance, insulin secretion etc. As well as our further analysis of the nature of islet-resident macrophages and their impact to beta cell function and proliferation.