Supported data for "Investigating the Pathological Mechanisms for the Spread of α-Synuclein in Experimental Parkinson’s Disease"

<p dir="ltr">Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. Loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and Lewy bodies in neurons are two major pathological hallmarks of the PD. The spread of a-synuclein to other brain regions has been speculated to induce neuronal death and loss of some brain functions. However, it is still a major question in PD research field. While free radicals play an important role in the pathogenesis of PD, it is unclear whether this factor also makes impact on the spreading of a-synuclein to other brain regions. This study aims to investigate whether free radicals affect the spread of a-synuclein in experimental models of PD. This data set includes data presented in the result chapters.</p>