Supporting data for "Big Data Omics Analysis Guided Discovery of Bacteriocins from the Human Microbiome"

Bacteriocins are ribosomally synthesized antimicrobial peptides produced by bacteria, exhibiting diverse structures from post-translationally modified to linear forms. Their diversity and potency make them promising alternatives or adjuncts to antibiotics in combating antimicrobial resistance. Beyond mediating microbe-microbe interactions, bacteriocins may engage with the human host, underscoring the importance of exploring human microbiome-derived bacteriocins and their health implications. Although the traditional activity-based screening approach identifies diverse bacteriocins from the human microbiome, they remain largely untapped in the meta-omics era. Therefore, exploring human microbiome-derived bacteriocins can expand the antimicrobial arsenal and deepen insights into their roles in human health.

The datasets provide the support data for "Big Data Omics Analysis Guided Discovery of Bacteriocins from the Human Microbiome". Two separate folders, Dataset (Chapter 2) and Dataset (Chapter 3) support the studies of Chapter 2 and Chapter 3, respectively