Supporting data for " Block Co-polymer Metal Organic Cage Micelles: Towards Unimolecular, Atomically Precise and Highly Addressable Composite Nanoparticles"
The dataset includes original record of experimental protocols, raw data, and analyzed figures for thesis. It's also accompanied with research slides from our regular group meeting. The thesis describes the synthesis of atomcially precise nanoparticles and their applications in nanomedicine, which is assembled via a directed, stepwise strategy by integrating metal-organic polydedral complexes and sequence defined peptoids. The dataset contains a variety of original data that support the thesis. For example, the NMR and LC-MS help to identify the small molecular, polymers and peptoids. The Uv-vis can characterize the structure integrity of metal-organic complexes. DLS and TEM are used to measure their sizes and morphologies. Native mass spectroscopy can identify the atom-precision features of the nanoparticle. Fluorescence is used to measure the critical micelle concentration and fluorescence resonance energy transfer. Research slides regarding to the projects are also shared.
Funding
Start-up fund of The University of Hong Kong
General Research Fund (GRF) of the Research Grant Council (RGC) of Hong Kong (project No. 17308518)