This file contains datasets for two clinical studies, namely "Effect of denture adhesives on masticatory function of extensive partial denture wearers: a clinical trial", and "Effects of oral exercises on the masticatory performance and rehabilitation of stroke patients: a randomized controlled trial". IRB approvals, data collection forms (Excel files), SPSS datasets for statistical analysis, GraphPad dataset for generating figures, for both clinical studies, were all contained in this file.