HKU Data Repository

All raw and processed data

Reason: All the data in dataset are unpublished. Also, the data are related to findings that can be commercialized in future.

Supporting data for "Dendrimer nanoparticles in anticancer treatment applications"

posted on 2021-12-21, 02:15 authored by Margarita Artemenko, Alice Sze Tsai WongAlice Sze Tsai Wong
This data is used in the PhD thesis "Dendrimer nanoparticles in anticancer treatment applications" and contain the findings about in vitro and in vivo efficacy and toxicity of dendrimer-enhanced small molecules and siRNAs. We used dendrimer nanoparticles as anti-LMP1 siRNA carriers for nasopharyngeal carcinoma targeted therapy, and applied bola-lipid dendrimers as vehicles for imatinib mesylate to successfully inhibit ovarian cancer stem cells, both in vitro and in vivo, without serious adverse effects.