Dataset (main folder)
Reason: The manuscripts are still under preparation.
Supporting data for "Effect of Radix Rehmanniae and its active compounds against neurological autoimmune disease through regulating oxidative stress-induced immunodysfunction"
This folder contains the data obtained for the thesis entitled "Effect of Radix Rehmanniae and its active compounds against neurological autoimmune disease through regulating oxidative stress-induced immunodysfunction", including the FACS data, immunohistochemical images, and the relevant quantification and analysis of data. This research is to study the peroxynitrite-mediated Tregs reduction and dysfunction in the periphery immune system could be a critical pathological process to aggravating Th1/Th17 infiltration and CNS damage in MS/EAE pathogenesis. Moreover, we found Rehmannioside D and Acteoside , natural medicinal compounds from RR, promoted Treg/Breg and reduced T effector cells, thus amelirating autoimmune disease.