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Supporting data for "Effect of Radix Rehmanniae and its active compounds against neurological autoimmune disease through regulating oxidative stress-induced immunodysfunction"

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posted on 2022-10-07, 01:38 authored by Meiling WuMeiling Wu

This folder contains the data obtained for the thesis entitled "Effect of Radix Rehmanniae and its active compounds against neurological autoimmune disease through regulating oxidative stress-induced immunodysfunction", including the FACS data, immunohistochemical images, and the relevant quantification and analysis of data. This research is to study the peroxynitrite-mediated Tregs reduction and dysfunction in the periphery immune system could be a critical pathological process to aggravating Th1/Th17 infiltration and CNS damage in MS/EAE pathogenesis. Moreover, we found  Rehmannioside D  and Acteoside  ,  natural medicinal compounds from RR, promoted Treg/Breg and reduced T effector cells, thus amelirating autoimmune disease. 

Funding

Research Grants Council grant (AoE/P-705/16)

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