Supporting data for “Elucidating the Pathogenesis of Enterovirus A71 Infection Using a Multi-omics Approach”

Enterovirus A71 (EV-A71) is an important human-pathogenic virus that causes hand, foot, and mouth disease (HFMD) outbreaks. Severe EV-A71 infection may be associated with neurological and cardiopulmonary complications which have a high mortality. However, the pathogenesis underlying these severe complications is not fully understood and effective antiviral treatment for EV-A71 infection is unavailable currently. Lipidomics and metabolomics applied in this study aimed to provide insights on EVA-71-induced changes on the host lipidome and metabolome and advance the knowledge of EV-A71 pathogenesis and the development of treatment strategy against EV-A71 infection.

The dataset is organized into two individual folders. Each of them includes all the dataset for the lipidomic and metabolic studies in my PhD thesis separately. The raw data of lipidomics, metabolomics, and RT-qPCR which contains name of samples, identified compounds, date of experiment, and treatments are reserved in the dataset. Other summarized data of experiments with different treatments are all shown in the dataset.