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Supporting data for “Halogen Bond-Catalyzed Friedel-Crafts, Povarov and Aziridine Ring-Opening Reactions”.

posted on 12.01.2022, 12:54 by Xuelei Liu

Halogen bond has been studied and applied in many fields, the use of halogen bond in the field of organocatalysis has only been reported in recent years. This study aims to extend the halogen bond catalysis with novel halogen bond donors and apply them as catalysts into many new contexts, including Friedel-Crafts reaction, Povarov reaction, and Aziridine ring-opening reaction. Many natural compounds such as arsindoline A, trisindoline, arundine, and vibrinddole A with interesting bioactivities were synthesized in high yields using the designed halogen bond donor catalysts.

This dataset consists of detailed experimental procedures, mass spectrometry, and nuclear magnetic resonance spectroscopy.


Research Grants Council of the Hong Kong S. A. R., P.R. China (Project GRF 17307518)


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