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Supporting data for "Hepatocyte Clonal Expansion And Hepatitis B Virus DNA Integration In Patients With Long-Term Nucleos(t)ide Analogue Therapy"

posted on 22.09.2021, 14:36 authored by Ning ChowNing Chow

One proposed mechanism of chronic hepatitis B (CHB) infection induced hepatocellular carcinoma (HCC) is via the integration of hepatitis B virus (HBV) DNA into the host genome. In this thesis, we used inverse PCR to investigate the HBV DNA integration in 28 CHB patients. We identified nearly 800 integration events and they were listed in this dataset.