Supporting data for "Human Induced Pluripotent Stem Cell-Based Models of Congenital Diseases: Hirschsprung Disease and Congenital Central Hypoventilation Syndrome"

Supporting data for the thesis "Human Induced Pluripotent Stem Cell-Based Models of Congenital Diseases: Hirschsprung Disease and Congenital Central Hypoventilation Syndrome".

Includes raw flow cytometry data in .fsc format, raw luciferase data in .xls file, raw Western blot data & EMSA data in .tiff format, raw real-time qPCR in .xls format and raw ddPCR data file, phase-contrast image of hBOs in TIFF/JPEG format, immunofluorescence (IF) images in TIFF/JPEG format.

ImageJ(Fiji) were used for image analyses. Microsoft Excel and Graphpad Prism 9 were used for statistical analyses. Prism files (.pzfx) summarizing all the quantification data were included in each folder.

Published articles of the thesis:

1. Review article about stem cell-based cell model in Chapter 1 - DOI: 10.1055/s-0038-1646925

2. scRNA-seq analyses of hiPSC-derived ENS models & E13.5 mouse ENCCs and HCO data in Chapter 3 - DOI: 10.1053/j.gastro.2019.08.019

3. Whole-genome sequence data of S-HSCR patients in Chapter 4 & 5 - DOI: 10.1053/j.gastro.2018.09.012

4. Study of HSCR-associated non-coding variants in Chapter 4 & 5 - DOI: 10.1101/gr.264473.120