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Classical memory and exhausted B cells in LN, genetic dysregulation in LN

Reason: The datasets include confidential and sensitive data collected from Hong Kong patients' blood samples, containing patient information.

Supporting data for “Perturbations in the Frequency and Function of Exhausted and Classical Memory B cells – Role in Systemic lupus Erythematosus and Lupus Nephritis”

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posted on 2024-07-09, 08:50 authored by Litong ZhuLitong Zhu

This dataset indicates that alterations in the number and function of classical and exhausted memory B cells may be associated with the risk of lupus nephritis (LN) relapse. Additionally, genetic dysregulations in exhausted and classical memory B cells can affect their homeostasis, thereby influencing the development of autoimmune diseases such as systemic lupus erythematosus (SLE) and LN.

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