Supporting data for "Radix Rehmanniae and Active Ingredients Ameliorate CFA-Induced Inflammation by Attenuating Macrophage-Mediated Localized Response and Nitrative Damage"

<p>This research highlights that macrophage-induced inflammation leads to localized nitration and assembly, contributing to tissue damage and inflammatory cell infiltration in OA pathogenesis. </p><p>Targeting macrophage-mediated inflammation offers a promising OA therapeutic strategy. RR and its active ingredients show potential as therapeutic agents to alleviate macrophage-mediated localized inflammatory microenvironments and nitrative damage in OA treatment.</p><p>Further investigations are warranted to comprehend the precise mechanisms and clinical applicability of RR and its active compounds in managing inflammatory pain and OA.</p>