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Supporting data for "Rational design and development of an interferon-integrated universal sarbecovirus vaccine"

dataset

posted on 2024-09-12, 01:15 authored by Derek Tsz Yin CheungDerek Tsz Yin Cheung

This is a complete dataset for the thesis "Rational design and development of an interferon-integrated universal sarbecovirus vaccine"

In this study we designed a SARS-CoV-2 vaccine platform, which is interferon-beta integrated vaccine (IBIS). The designed different versions for different purposes. The vaccines were able to elicit robust antibody responses and completely protect hamsters from SARS-CoV-2 infection without causing lung pathology. The vaccine seeds and producing cell-line are generated and ready for future human trial.

In the dataset folders, there are three subfolders. Inside each subfolder, there is a folder for each experiment. Inside the experiment folder, there are protocol and corresponding data. README.txt file was provided for the description of the datasets.