Supporting data for “Regulation of macrophage polarization and osteoblastic cellular behaviours on titanium surface through the design of surface pattern that facilitates implant-to-bone osteointegration”

The modulatroy role of specific surface topographies on macrophages and osteoblastic cells.

Part 1. Modulatory role of Tsurface structures on osteoblasts cellular behaviours.

1. surface characterizations
2. fluorecent staining and quatification of cells,
3. cell morphologies
4. in vitro investigation of osteoblasts cellular behaviours
5. in vivo investigation of bone-to-implant integration
6. shcematic diagrams

Part 2. Regulation of macrophage polarization that facilitates implant-to-bone osteointegration

1. surface characterizations
2. macrophage morphologies
3. macrophage polarization
4. osteogenic differentiation of MSCs
5. in vivo investigation of bone-to-implant integration
6. transcriptomics ans WB
7. schematic diagram