Supporting data for "Resistance to tyrosine kinase inhibitor (TKI) confers an immunosuppressive microenvironment and cross-resistance to immunotherapy through intratumoral AXL/PDPK1 signaling axis in liver cancer"

The dataset consists of data generated from the study titled " Resistance to tyrosine kinase inhibitor (TKI) confers an immunosuppressive microenvironment and cross-resistance to immunotherapy through intratumoral AXL/PDPK1 signaling axis in liver cancer", including data from in vivo animal experiments and in vitro functional assays.

The file named "Flow cytometry" includes representative data (.pptx) from flow cytometry analysis, including the Annexin V - PI apoptosis assay, mitoSOX staining assay, and the cell membrane calretuculin staining assay, together with the statistical analysis file (.pzfx) using prism graphpad. The file named "ATP" includes representative data for the extracellular ATP measurement from ATP assay. The file contains a sample assay data in .xlsx format generated from the Perkin Elmer plate reader, together with a .pzfx file containing statistical analysis. The file named "Immunohistochemistry (IHC)" contains a pptx. file containing representative images of the IHC staining data, together with a pzfx. file for statistical analysis. The file named "real-time qPCR" contains data generated from Roche LightCycler480 qPCR analyzer, including a xlsx. file for representative row data and a pzfx. file for statistical analysis. The file named "Animal experiments" contains data from in vivo animal experiments. A pptx. file containing the representative data for mouse tumor progression and a pzfx. file for statistical analysis are included.