<p>This thesis consists of the following chapters,</p>
<p>- Chapter 1 General Introduction</p>
<p>- Chapter 2 Developmental trajectories of gut microbiota in infancy</p>
<p>- Chapter 3 Delayed gut microbiota development and childhood allergy</p>
<p>- Chapter 4 Early gut microbiota maturation mediates the effect of maternal smoking during pregnancy on childhood overweight</p>
<p>- Chapter 5 Construction and applications of human early-life gut bacteriome and virome databases</p>
<p>- Chapter 6 Summary and Perspective</p>
<p>Chapters 2-4 were based on the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort (https://childstudy.ca/), where access to individual-level participant data is controlled.</p>
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<p>This dataset only contains supporting data for Chapter 5, which was aggregated from public databases or papers freely, or was generated by the authors of this study.</p>