Supporting data for study of HSCR-associated mutations
Reason: Unpublished data.
Supporting data for “Study of the effect of Hirschsprung disease associated ephrinA1 and EphB2 mutations on cell-cell interaction“
datasetposted on 2022-01-12, 04:04 authored by Wing Lam ChanWing Lam Chan
Thesis figures and quantification data for the thesis entitled "Study of the effect of Hirschsprung disease associated ephrinA1 and EphB2 mutations on cell-cell interaction".
The study aimed at investigating the functional role of Eph/ephrin signaling on ENCC colonization, the impact of the ephrinA1 and EphB2 mutations identified in Hirschsprung disease patients on cell-cell interaction and Eph/ephrin signaling mechanism. Stripe assay is used to examine the response of migraeting ENCCs upon interaction with Ephs and ephrins. Segregation assay is used to investigate the influence of the identified mutations on cell-cell interaction.