Supporting data for The Functional Roles of SCD1/FADS2 Lipid Desaturases in Modulating Lipid Metabolic Activities and Redox-driven Ferroptosis in Ascites-derived Ovarian Cancer Cells

<p>1. The desaturation abilities of SCD1/FADS2 are aberrantly augmented in ascites-derived ovarian cancer cells.</p><p>2. SCD1/FADS2 causes the elevation of poly- and mono-unsaturated fatty acids (UFAs) and <a></a><a>enhanced oncogenic properties of</a> ovarian cancer cells.</p><p>3. SCD1/FADS2 modulates GSH/GSSG ratio and GPX4, preventing induction of ferroptosis.</p><p>4.Targeting suppression of SCD1/FADS2 synergistically enhances cisplatin-mediated cytotoxicity in ascites-derived ovarian cancer cells.</p>