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Supporting data for "The Impact of Alterations in the Gut Microbiome on the Immunopathogenesis of Diabetic keratopathy "
dataset
posted on 2022-02-21, 06:45 authored by Yashan BuThe dataset contains all thesis-related data. It is divided according to the year the data have been collected. In each folder, the data are separated based on the experiments they were used for.
Our
findings revealed that, in diabetic mice, impaired cornea wound healing was
associated with a significant inability to mount a proper systemic and local
immune response to ocular chemical injury. Baseline and post-injury differences
in intestinal microbial diversity and abundance patterns between diabetic mice
and controls may account for this impaired response. Importantly, probiotics
treatment has been demonstrated to be a novel and promising therapeutic agent
in treating diabetic keratopathy
