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Supporting data for "The essential role of male germline-specific protein MAPS in pachynema progression and fertility"

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posted on 2023-10-27, 08:29 authored by Jiahuan Zheng

Meiosis enables the generation of haploid gametes from corresponding diploid progenitor cells with high fidelity and ensures genetic diversity through recombination. Meiotic prophase I, as a critical element of gametogenesis, is classified into five stages based on the chromosomal configurations, namely leptotene, zygotene, pachytene, diplotene, and diakinesis stages. Various proteins are recruited and degraded in the complicated process in meiotic prophase I; however, the identified proteins are still limited. In this study, we identified a male pachynema-specific protein (Maps) gene, expressed specifically in the mouse testis and pachytene spermatocytes. The function and mechanism of MAPS in regulating pachynema progression were investigated.

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