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Supporting data for ''Towards Glycoprotein Synthesis via Chemical Ligation''

posted on 2021-08-17, 02:12 authored by Hongxiang WuHongxiang Wu, Xuechen LiXuechen Li

In this dataset, we present the first chemical synthesis of glycosylated adiponectin collagenous domains with all possible 15 glycoform combinations and PD-1 extracellular domain via chemical ligation approaches.

It includes the fully synthesizing details of the glycosylated Fmoc-protected hydroxyl-lysine building block and the construction of glycosylated adiponectin collagenous domains analogues. Moreover, we shows the synthetic steps and protocols for extracellular domain of the PD-1 protein.


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