HKU Data Repository


Reason: Not yet published.

Supporting data for "Transcriptomic and Functional Analysis of Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Tetralogy of Fallot Patient with and without DiGeorge Syndrome"

posted on 2021-09-15, 06:42 authored by Chun Ho Chan
Whole genome sequencing was performed on the human induced pluripotent stem cells (hiPSC) derived from tetralogy of Fallot (TOF) patients with or without DiGeorge Syndrome. Single cell RNA sequencing were then subsequently performed on the cardiac progenitors and the cardiomyocytes (CM) derived from patient-specific hiPSC. The electrophysiological profile of patient-specific-hiPSC-CM was assessed with the construction of cardiac anisotropic sheet (CAS).