Supporting data for the "The role of tumor-derived lipid metabolites in the immune microenvironment of hepatocellular carcinoma"

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, characterized by complex molecular alterations and immunosuppressive tumor microenvironment (TME) formation. Recent studies have highlighted the critical role of lipid metabolic reprogramming in shaping TME, promoting tumor progression, and resistance to immune checkpoint blockades (ICBs) therapy. However, the crosstalk regulators between tumor cells and immune cells, rewiring the anti-tumor immunity in HCC TME remain poorly understood.

The Dataset includes three folders.

Folder 1: Clinical data and Quantitative analysis of HCC tissue arrays.

Folder 2: H&E Staining, Immunohistochemistry Raw Data, and Multiplex Immunohistochemistry Images of HCC tissue arrays. The Multiplex Immunohistochemistry Images were divided into five parts.

Folder 3: Images of monitoring tumor growth of HCC mouse models.