Supporting data for the thesis "Oxidative distress and dipeptidyl peptidase-4 inhibitors mediated Nrf2 redox modulation in murine periodontitis"

This supporting data includes schematic diagram, western blotting, flowchart, qRT-PCR, immunofluorescence, alizarin red S staining, Flow cytometric analysis, TRAP staining, H&E staining, GO analysis, micro-CT analysis, SEM images, TEM images and immunohistochemistry staining. Additionally, it presents a comprehensive analysis of the RNA sequencing data obtained from the murine experiments. It details the experimental design, methods used for RNA extraction, sequencing protocols, and data preprocessing steps. The analysis encompasses the identification of differentially expressed genes (DEGs) and their functional annotation. Key signaling pathways and gene networks implicated in periodontitis and its modulation by DPP4 inhibitors are elucidated. Additionally, the study explores the impact of diabetic conditions on gene expression profiles and investigates the role of oxidative stress and inflammation in periodontal tissue.