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Supporting data of "REDUCTIVE DESYMMETRIZATION OF MALONIC ESTERS TOWARDS α-TERTIARY AMINES, TERTIARY ALCOHOLS, AND 4,4’-BIS(OXAZOLINE) LIGAND SCAFFOLDS"

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posted on 2025-03-28, 07:03 authored by Ho Man LauHo Man Lau
<p dir="ltr">The two dataset files contain the data for my PhD thesis entitled "Reductive desymmetrization of malonic esters towards α-tertiary amines, tertiary alcohols, and 4,4’-bis(oxazoline) ligand scaffolds”. In this research, various α-tertiary amines, α-tertiary alcohols and important organic compounds derived from α-tertiary amines and α-tertiary alcohols have been synthesised in the first chapter of the study. On the other hand, several 4,4’-bis(oxazoline) ligands have been derived from the bis(β-hydroxyesters) obtained from double desymmetrization of bis(malonic esters).</p><p dir="ltr">The 1st file contains the experimental procedures, recorded data from <sup>1</sup>H NMR, <sup>13</sup>C NMR, Infrared, ESI-MS spectra in Chapter 3 - <b>Synthesis of</b><b>-Amino- and</b><b> </b><b>-Oxy</b><b>-Hydroxyesters from Malonic </b><b>Esters via Dinuclear Zinc-catalysed Desymmetric Reduction </b>and Chapter 4 - <b>Synthesis and Applications of 4,4’-Bis(oxazoline) (4,4’-BOX) Ligand </b><b>via Dinuclear Zinc-catalysed Double Desymmetric Reduction of Bis(malonic esters)</b>.</p><p dir="ltr">The 2nd file contains the spectral data of chiral HPLC spectra in Chapter 3 - <b>Synthesis of</b><b>-Amino- and</b><b> </b><b>-Oxy-</b><b>-Hydroxyesters from Malonic </b><b>Esters via Dinuclear Zinc-catalysed Desymmetric Reduction </b>and Chapter 4 - <b>Synthesis and Applications of 4,4’-Bis(oxazoline) (4,4’-BOX) Ligand </b><b>via Dinuclear Zinc-catalysed Double Desymmetric Reduction of Bis(malonic esters)</b>.</p>

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