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Tuesday Seminar_Tang Kaiming_5 Nov 2024.pdf (5.12 MB)
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aa alignment CoVs PLpro.png (419.21 kB)
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CLUSTALW Result SARS-CoV-2 Variant sequence similarity %.pdf (74.16 kB)
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SARS-CoV-2 variants PLpro.txt (1.72 kB)
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Supporting data for "DEVELOPMENT OF ANTIVIRAL AGENTS AGAINST SARS-CoV-2 PROTEASES"

dataset
posted on 2024-11-28, 02:28 authored by Kaiming TangKaiming Tang, Shuofeng YuanShuofeng Yuan

This study aims to develop novel antivirals against SARS-CoV-2 papain-like protease and main protease by high-throughput screening and in silico structure-based screening of large-scale compound libraries, respectively. Hit compounds were selected for further studies such as in vitro and in vivo antiviral potency and mechanistic investigations. This dataset includes the raw/processed data and figures of the abovementioned results.

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