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Supporting data for "Cell cycle inhibitors for liver cancer treatment"

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posted on 2022-09-09, 03:19 authored by Po Yee WongPo Yee Wong

  

A.  Data showing the gene expression level of tubulin (TUBB), aurora kinase B (AURKB), CDK4 and CDK6 in HCC tissue and corresponding non-tumorous liver tissues (NT) in HCC patients. Scatter dot plot: mean with SD. Student’s t test: * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001.


B.  Data showing the correlation between HCC patients with normal or high expression level of TUBB, AURKB, CDK4 and DDX41 and the percentage of survival in overall survival l model. Log-rank (Mantel-Cox) test: * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001.


C.  Data showing the correlation between HCC patients with normal or high expression level of TUBB, AURKB and CDK4 and the percentage of survival in disease-free survival model. Log-rank (Mantel-Cox) test: * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001.


D. Data showing the aneuploidy score, Buffer hypoxia score and Winter hypoxia score of HCC patients with normal or high expression level of DDX41. Wilcoxon test: * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001.

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