This README.txt file was genertaed on 20201110, by Vimalagopalan divya General information regarding the data set submitted: 1. Title of the thesis: Genetic and mechanical interactions in the pathogenesis of adolescent idiopathic scoliosis. 2. Author information: First author: Divya, Vimalagopalan Faculty: Medicine Email: divyav@hku.hk 3. File overview: Folder 1: X-ray data Incudes X-ray images in jpeg/tif format, easily readable. File includes whole mount X-rays, tail X-rays, and tail looping X-rays. XL sheet of X-ray analysis done through ImageJ software. Folder 2: Histology data Includes raw histological images in Jpeg/tiff format, easily readable. Includes IVD histology, growth plate histology, limb histology and tail looping histology. XL sheet of histology analysis measuring area, volume, disc height and disc length. Folder 3: Immunofluorescence data (IF) IF images in tiff format includes seperate channels and merged channels. IF staining for Pax1(red), Sox9(green), Collagen 1(green)/2(red), Dapi(blue) and Tunel assay (red). Folder 4: RPG presentation Inculdes PPT of presentation in RPG seminar and RPG poster in pdf files. 4. Software used for analysis ImageJ_open source software.